{"id":5494,"date":"2022-04-20T17:33:38","date_gmt":"2022-04-20T17:33:38","guid":{"rendered":"https:\/\/iboblr.in\/gupathsociety\/?page_id=5494"},"modified":"2022-10-28T06:17:00","modified_gmt":"2022-10-28T06:17:00","slug":"literarure-watch-2021","status":"publish","type":"page","link":"https:\/\/iboblr.in\/gupathsociety\/literarure-watch-2021\/","title":{"rendered":"Literarure Watch 2021"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"5494\" class=\"elementor elementor-5494\" data-elementor-settings=\"[]\">\n\t\t\t\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1d1f19e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1d1f19e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-0e2611d\" data-id=\"0e2611d\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5f79ea9 elementor-widget elementor-widget-sidebar\" data-id=\"5f79ea9\" data-element_type=\"widget\" data-widget_type=\"sidebar.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div id=\"block-5\" class=\"widget widget_block\" data-widget-id=\"block-5\"><div class=\"widget_wrap\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link\" href=\"https:\/\/iboblr.in\/gupathsociety\/literature-watch-2022\/\">Literature Watch 2022<\/a><\/div>\n<\/div>\n<\/div><\/div>\n<span class=\"widget_corner\"><\/span><\/div><\/div><div id=\"block-25\" class=\"widget widget_block\" data-widget-id=\"block-25\"><div class=\"widget_wrap\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<span class=\"widget_corner\"><\/span><\/div><\/div><div id=\"block-6\" class=\"widget widget_block\" data-widget-id=\"block-6\"><div class=\"widget_wrap\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link\" href=\"https:\/\/iboblr.in\/gupathsociety\/literarure-watch-2021\/\">Literature Watch 2021<\/a><\/div>\n<\/div>\n<\/div><\/div>\n<span class=\"widget_corner\"><\/span><\/div><\/div><div id=\"block-26\" class=\"widget widget_block\" data-widget-id=\"block-26\"><div class=\"widget_wrap\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<span class=\"widget_corner\"><\/span><\/div><\/div><div id=\"block-24\" class=\"widget widget_block\" data-widget-id=\"block-24\"><div class=\"widget_wrap\">\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link\" href=\"https:\/\/iboblr.in\/gupathsociety\/literature-watch-2020\/\">Literature Watch 2020<\/a><\/div>\n<\/div>\n<span class=\"widget_corner\"><\/span><\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-a51a81e\" data-id=\"a51a81e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-850042e elementor-widget elementor-widget-html\" data-id=\"850042e\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<script>\r\njQuery(document).ready(function($) {\r\nvar delay = 100; setTimeout(function() {\r\n$('.elementor-tab-title').removeClass('elementor-active');\r\n $('.elementor-tab-content').css('display', 'none'); }, delay);\r\n});\r\n<\/script>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5b1d654 elementor-widget elementor-widget-accordion\" data-id=\"5b1d654\" data-element_type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.5.6 - 28-02-2022 *\/\n.elementor-accordion{text-align:left}.elementor-accordion .elementor-accordion-item{border:1px solid #d4d4d4}.elementor-accordion .elementor-accordion-item+.elementor-accordion-item{border-top:none}.elementor-accordion .elementor-tab-title{margin:0;padding:15px 20px;font-weight:700;line-height:1;cursor:pointer;outline:none}.elementor-accordion .elementor-tab-title .elementor-accordion-icon{display:inline-block;width:1.5em}.elementor-accordion .elementor-tab-title .elementor-accordion-icon svg{width:1em;height:1em}.elementor-accordion .elementor-tab-title .elementor-accordion-icon.elementor-accordion-icon-right{float:right;text-align:right}.elementor-accordion .elementor-tab-title .elementor-accordion-icon.elementor-accordion-icon-left{float:left;text-align:left}.elementor-accordion .elementor-tab-title .elementor-accordion-icon .elementor-accordion-icon-closed{display:block}.elementor-accordion .elementor-tab-title .elementor-accordion-icon .elementor-accordion-icon-opened,.elementor-accordion .elementor-tab-title.elementor-active .elementor-accordion-icon-closed{display:none}.elementor-accordion .elementor-tab-title.elementor-active .elementor-accordion-icon-opened{display:block}.elementor-accordion .elementor-tab-content{display:none;padding:15px 20px;border-top:1px solid #d4d4d4}@media (max-width:767px){.elementor-accordion .elementor-tab-title{padding:12px 15px}.elementor-accordion .elementor-tab-title .elementor-accordion-icon{width:1.2em}.elementor-accordion .elementor-tab-content{padding:7px 15px}}<\/style>\t\t<div class=\"elementor-accordion\" role=\"tablist\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-9551\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"tab\" aria-controls=\"elementor-tab-content-9551\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" href=\"\">Literature Watch 2020 Q1<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-9551\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-9551\"><h3 align=\"center\">Literature Watch &amp; News: Genitourinary Pathology (2020 Q1)<\/h3><p align=\"center\">Sounak Gupta, MBBS, PhD and Rohit Mehra, MD<\/p><h3 style=\"background-color: #e1e1e1; margin: 10px 0px 10px 0px; padding: 10px 0px 10px 10px;\">Renal Cancer<\/h3><p><strong>Recurrent KRAS mutations in papillary renal neoplasm with reverse polarity<\/strong>.<\/p><p>Al-Obaidy KI et al. Modern Pathology. 2019 Sep 18. PMID: 31534204.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31534204\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31534204<\/a><\/p><p>&#8211; This study, senior authored by the late Dr. David Grignon, a giant in the field of genitourinary pathology, is another seminal work which characterizes the morphologic features and molecular underpinnings of a unique variant of papillary renal cell carcinoma.<\/p><p><strong>&#8220;Renal Cell Carcinoma With Leiomyomatous Stroma&#8221; Harbor Somatic Mutations of TSC1, TSC2, MTOR, and\/or ELOC (TCEB1): Clinicopathologic and Molecular Characterization of 18 Sporadic Tumors Supports a Distinct Entity.<\/strong><\/p><p>Shah RB et al. American Journal of Surgical Pathology. 2019 Dec 31. PMID: 31850909.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31850909\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31850909<\/a><\/p><p>&#8211; The authors of this study provide insight into the characterization of renal neoplasms that are morphologically enriched for the presence of leiomyomatous stroma, including underlying molecular alterations.<\/p><h3 style=\"background-color: #e1e1e1; margin: 10px 0px 10px 0px; padding: 10px 0px 10px 10px;\">Bladder Cancer<\/h3><p><strong>BCG is extensively used for the management of non-muscle invasive bladder cancer. However, significant shortages are anticipated in the coming year. This has been highlighted by the Bladder Cancer Advocacy Network (BCAN): <\/strong><\/p><p><a href=\"https:\/\/bcan.org\/bcg-shortage-bladder-cancer\/#1560949642874-aab3abc1-db8e\">https:\/\/bcan.org\/bcg-shortage-bladder-cancer\/#1560949642874-aab3abc1-db8e\/<\/a><\/p><p>\u00a0<\/p><h3 style=\"background-color: #e1e1e1; margin: 10px 0px 10px 0px; padding: 10px 0px 10px 10px;\">Prostate Cancer<\/h3><p><strong>When and How Should Active Surveillance for Prostate Cancer be De-Escalated? <\/strong><\/p><p>Rajwa P et al. European Urology Focus. 2020. https:\/\/doi.org\/10.1016\/j.euf.2020.01.001<\/p><p><a href=\"https:\/\/doi.org\/10.1016\/j.euf.2020.01.001\">https:\/\/doi.org\/10.1016\/j.euf.2020.01.001<\/a><\/p><p>&#8211; Herein, the authors review available evidence and guidelines addressing transitions from active to passive monitoring for patients with low-risk prostate cancer.<\/p><p>\u00a0<\/p><p><strong>Reporting Practices and Resource Utilization in the Era of Intraductal Carcinoma of the Prostate: A Survey of Genitourinary Subspecialists. <\/strong><\/p><p>Gandhi JS et al. American Journal of Surgical Pathology. 2019 Dec 23. PMID: 31876580.<\/p><p><a href=\" https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31876580\"> https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31876580<\/a><\/p><p>This report summarizes best practice recommendations related to diagnosis and reporting practices pertaining to intraductal carcinoma of the prostate.<\/p><p>\u00a0<\/p><p><strong>Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019.<\/strong><\/p><p>Gillessen S et al. European Urology. 2020 Jan 27. PMID: 32001144.<\/p><p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32001144\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32001144<\/a><\/p><p>This study summarizes expert opinion related to common issues and controversies regarding the management of patients with advanced prostate cancer, including metastatic hormone-sensitive and metastatic castration-resistant prostate cancer.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-9552\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"tab\" aria-controls=\"elementor-tab-content-9552\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" href=\"\">Literature Watch 2020 Q2<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-9552\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-9552\"><h3 align=\"center\"> Literature Watch &#038; News: Genitourinary Pathology (April 2020- Lockdown edition)<\/h3>\n<p align=\"center\">Sounak Gupta, MBBS, PhD and Rohit Mehra, MD.<\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Renal Cancer<\/h3>\n \n\n<p><strong>MiT family translocation renal cell carcinoma. <\/strong><\/p>\n<p>Argani P. Semin Diagn Pathol. 2015 Mar;32(2):103-13. Review. PMID: 25758327.&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25758327\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25758327<\/a><\/p>\n<p>&#8211; This review, authored by Dr. Pedram Argani, highlights the morphologic, translational and biologic features of MiT family aberration renal cell carcinoma.<\/p>\n\n\n<p><strong> Contemporary Renal Tumor Categorization With Biomarker and Translational Updates: A Practical Review. <\/strong><\/p>\n<p>Taylor et al. Arch Pathol Lab Med. 2019 Dec;143(12):1477-1491. Review. PMID: 31765248. &nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31765248\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31765248<\/a><\/p>\n<p>&#8211; The authors of this study provide insight into the evolutionary biomarker landscape of renal cell carcinoma, incorporating established markers with upcoming markers of clinical potential.<\/p>\n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Bladder Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>Updates on the Genomics of Bladder Cancer and Novel Molecular Taxonomy. <\/strong><\/p> \n <p>Al-Ahmadie H, Netto GJ. Adv Anat Pathol. 2020 Jan;27(1):36-43. Review. PMID: 31743118.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31743118\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31743118<\/a><\/p>\n<p>This review provides an update on the recent advances in the molecular characterization and novel molecular taxonomy of urothelial carcinoma and its histologic variants.<\/p>\n \n\n \n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Prostate Cancer<\/h3>\n \n<p><strong>Knowing what&#8217;s growing: Why ductal and intraductal prostate cancer matter.<\/strong><\/p>\n<p>Lawrence et al. Sci Transl Med. 2020 Mar 4;12(533). Review. PMID: 32132214.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32132214\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32132214\/<\/a><\/p>\n<p>&#8211; This review summarizes the pathologic, clinical and translational implications of ductal prostate cancer and intraductal prostate cancer.<\/p>\n<p><br>\n<\/p>\n\n<p><strong>Towards precision oncology in advanced prostate cancer. Ku et al. Nat Rev Urol. 2019 Nov;16(11):645-654. Review. PMID: 31591549. <\/strong><\/p> \n<p><a href=\" https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31591549\"> https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31591549<\/a><\/p>\n<p>This review summarizes expert opinion related to concepts, common management issues and clinical applications for patients with advanced prostate cancer. <\/p>\n \n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Testis Cancer<\/h3>\n<p><strong>Recently Described and Clinically Important Entities in Testis Tumors: A Selective Review of Changes Incorporated Into the 2016 Classification of the World Health Organization. <\/strong><\/p>\n<p>Ulbright TM. Arch Pathol Lab Med. 2019 Jun;143(6):711-721. Review. PMID: 29949388.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29949388\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29949388\/<\/a><\/p>\n<p>&#8211; This review summarizes some common testicular pathologies with their clinical implications especially in light of the WHO classification of genitourinary tumors.<\/p>\n \n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Penile Cancer<\/h3>\n<p><strong>Pathology of Invasive and Intraepithelial Penile Neoplasia. <\/strong><\/p>\n<p>Canete-Portillo et al. Eur Urol Focus. 2019 Sep;5(5):713-717. Review. PMID: 31288989. <\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31288989\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31288989<\/a><\/p>\n<p>&#8211; This review summarizes an updated approach towards classification of penile intraepithelial neoplasia and penile invasive carcinoma.<\/p>\n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Miscellaneous<\/h3>\n<p><strong>Next generation immunohistochemistry: Emerging substitutes to genetic testing?<\/strong><\/p>\n<p>Andrici et al. Semin Diagn Pathol. 2018 May;35(3):161-169. Review.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28662997\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28662997<\/a><\/p>\n<p>PMID: 28662997<\/p>\n<p>&#8211; This review elaborates on the utility of immunohistochemistry in detection of syndromic neoplasia (including genitourinary) from a surgical pathology perspective.<\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Complimentary Courses<\/h3>\n\n<strong>USCAP:&nbsp;<\/strong>Urologic Pathology, Course Director: Adeboye O. Osunkoya, MD<br>\n<strong>Code:<\/strong>&nbsp;USCAPnvzcxw<br>\n<strong>&ldquo;Complimentary Access to eLearning from USCAP<\/strong>\n\n \n<p>In response to the impact of the COVID-19 pandemic on pathology education, USCAP is currently providing complimentary access to eLearning modules<\/p>\n<p><a href=\"https:\/\/www.pathlms.com\/uscap\/courses\/14759\">https:\/\/www.pathlms.com\/uscap\/courses\/14759<\/a><\/p>\n \n<p>This includes a section on Urologic Pathology, a course that is directed by Dr. Adeboye O. Osunkoya, MD, and includes sections on high yield prostate and bladder pathology (code: USCAPnvzcxw).\u201d<\/p>\n\n <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-9553\" class=\"elementor-tab-title\" data-tab=\"3\" role=\"tab\" aria-controls=\"elementor-tab-content-9553\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" href=\"\">Literature Watch 2021 Q3<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-9553\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-9553\"> <h3 align=\"center\">Literature Watch &#038; News: Genitourinary Pathology (July 2021)<\/h3>\n<p align=\"center\">Sounak Gupta, MBBS, PhD and Rohit Mehra, MD.<\/p>\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Kidney Cancer<\/h3>\n<p><strong>Improving Renal Tumor Biopsy Prognostication With BAP1 Analyses.<\/strong><\/p>\n<p>Kapur et al. Arch Pathol Lab Med (2021).<\/p>\n<p><a href=\"https:\/\/doi.org\/10.5858\/arpa.2020-0413-OA\">https:\/\/doi.org\/10.5858\/arpa.2020-0413-OA<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>EWSR1-PATZ1 fusion renal cell carcinoma: a recurrent gene fusion characterizing thyroid-like follicular renal cell carcinoma.<\/strong><\/p>\n<p>Al-Obaidy et al. Mod Pathol. 2021 Jun 7. doi: 10.1038\/s41379-021-00833-7. Online ahead of print. PMID: 34099871<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34099871\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34099871\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>A contemporary guide to chromosomal copy number profiling in the diagnosis of renal cell carcinoma.<\/strong><\/p>\n<p>Gupta et al. Urol Oncol. 2021 Jun 3:S1078-1439(21)00205-2. doi: 10.1016\/j.urolonc.2021.04.042. Online ahead of print. PMID: 34092479<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34092479\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34092479\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Low-Grade Oncocytic Tumor of Kidney (CK7-Positive, CD117-Negative): Incidence in a single institutional experience with clinicopathological and molecular characteristics.<\/strong><\/p>\n<p>Kravtsov et al. Hum Pathol. 2021 May 4;114:9-18. doi: 10.1016\/j.humpath.2021.04.013. Online ahead of print. PMID: 33961838<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33961838\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33961838\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Low-grade oncocytic tumour expands the spectrum of renal oncocytic tumours and deserves separate classification: a review of 23 cases from a single tertiary institute.<\/strong><\/p>\n<p>Akgul et al. J Clin Pathol. 2021 Jun 24:jclinpath-2021-207478. doi: 10.1136\/jclinpath-2021-207478. Online ahead of print. PMID: 34168073<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34168073\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34168073\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>SWI\/SNF-deficient neoplasms of the genitourinary tract.<\/strong><\/p>\n<p>Sirohi et al. Semin Diagn Pathol. 2021 May;38(3):212-221. doi: 10.1053\/j.semdp.2021.03.007. Epub 2021 Apr 3. PMID: 33840529<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33840529\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33840529\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Single-cell analyses of renal cell cancers reveal insights into tumor microenvironment, cell of origin, and therapy response.<\/strong><\/p>\n<p>Zhang et al. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2103240118. doi: 10.1073\/pnas.2103240118. PMID: 34099557<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34099557\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34099557\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Dataset for the reporting of nephrectomy specimens for wilms&rsquo; tumour treated with preoperative chemotherapy: recommendations from the international society of paediatric oncology renal tumour study group.<\/strong><\/p>\n<p>Histopathology. 2021 May 3. PMID:&nbsp; 33942359<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33942359\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33942359\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>TSC\/MTOR mutated eosinophilic renal tumors are a distinct entity that are CK7+\/CK20-\/vimentin-: a validation study.<\/strong><\/p>\n<p>Hum Pathol. 2020 Dec 19;S0046-8177(20)30259-8. PMID:&nbsp; 33352195.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33352195\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33352195\/<\/a><\/p>\n<p> <br> <\/p>\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Urinary Bladder Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>Molecular pathology of urothelial carcinoma.<\/strong><\/p>\n<p>Lopez-Beltran et al. Hum Pathol. 2021 Jul;113:67-83. doi: 10.1016\/j.humpath.2021.04.001. Epub 2021 Apr 19. PMID: 33887300 Review.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33887300\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33887300\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Urinary Large Cell Neuroendocrine Carcinoma: A Clinicopathologic Analysis of 22 Cases.<\/strong><\/p>\n<p>Wang et al. Am J Surg Pathol. 2021 Jun 2. doi: 10.1097\/PAS.0000000000001740. Online ahead of print. PMID: 34074810<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34074810\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34074810\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Molecular subtypes of upper tract urothelial cancer: Setting the stage for precision therapy.<\/strong><\/p>\n<p>McConkey et al. Cancer Cell. 2021 Jun 14;39(6):745-747. doi: 10.1016\/j.ccell.2021.05.004. PMID: 34129819<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34129819\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34129819\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><br>\n<\/p>\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Prostate Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>Advances in the selection of patients with prostate cancer for active surveillance.<\/strong><\/p>\n<p>Liu et al. Nat Rev Urol. 2021 Apr;18(4):197-208. doi: 10.1038\/s41585-021-00432-w. Epub 2021 Feb 23. PMID: 33623103<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33623103\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33623103\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>De novo neuroendocrine transdifferentiation in primary prostate cancer-a phenotype associated with advanced clinico-pathologic features and aggressive outcome.<\/strong><\/p>\n<p>Abdulfatah et al. Med Oncol. 2021 Feb 14;38(3):26. doi: 10.1007\/s12032-021-01473-2. PMID: 33586037<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33586037\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33586037\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Clinical Utility of Subclassifying Positive Surgical Margins at Radical Prostatectomy.<\/strong><\/p>\n<p>Dason et al. BJU Int. 2021 Jun 23. doi: 10.1111\/bju.15524. Online ahead of print. PMID: 34161656<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34161656\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34161656\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Association between BRCA2 alterations and intraductal and cribriform histologies in prostate cancer.<\/strong><\/p>\n<p>Lozano et al. Eur J Cancer. 2021 Apr;147:74-83. doi: 10.1016\/j.ejca.2021.01.027. Epub 2021 Feb 21. PMID: 33626496<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33626496\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33626496\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Extent of High-Grade Prostatic Adenocarcinoma in Multiparametric Magnetic Resonance Imaging-Targeted Biopsy Enhances Prediction of Pathologic Stage.<\/strong><\/p>\n<p>Arch Pathol Lab Med. 2021 May 20. PMID:&nbsp; 34015819<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34015819\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34015819\/<\/a><\/p>\n<p><br><\/p>\n \n \n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Testis Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>Circulating MicroRNAs, the Next-Generation Serum Biomarkers in Testicular Germ Cell Tumours: A Systematic Review.<\/strong><\/p>\n<p>Leao et al. Published:June 23, 2021DOI:https:\/\/doi.org\/10.1016\/j.eururo.2021.06.006<\/p>\n<p><a href=\"https:\/\/www.europeanurology.com\/article\/S0302-2838(21)01812-1\/fulltext\">https:\/\/www.europeanurology.com\/article\/S0302-2838(21)01812-1\/fulltext<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Comparative molecular analysis of testicular Leydig cell tumors demonstrates distinct subsets of neoplasms with aggressive histopathologic features.<\/strong><\/p>\n<p>Rizzo et al. Mod Pathol. 2021 Jun 8. doi: 10.1038\/s41379-021-00845-3. Online ahead of print. PMID: 34103665<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34103665\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34103665\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Discrepancy in pathology reports upon second review of radical orchiectomy specimens for testicular germ cell tumors.<\/strong><\/p>\n<p>Nason et al. Can Urol Assoc J. 2020 Dec;14(12):411-415. doi: 10.5489\/cuaj.6481. PMID: 32574142<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32574142\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32574142\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>SSX C-Terminus is a Useful Diagnostic Biomarker for Spermatocytic Tumour.<\/strong><\/p>\n<p>Anderson et al. Histopathology. 2021 May 7. doi: 10.1111\/his.14398. Online ahead of print. PMID: 33963590<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33963590\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33963590\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Histologic Findings in Surgical Pathology Specimens From Individuals Taking Feminizing Hormone Therapy for the Purpose of Gender Transition: A Systematic Scoping Review.<\/strong><\/p>\n<p>Arch Pathol Lab Med. 2021 May 13. PMID:&nbsp; 33983412.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33983412\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33983412\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Testicular Tumors: A Contemporary Update on Morphologic, Immunohistochemical and Molecular Features.<\/strong><\/p>\n<p>Adv Anat Pathol. 2021 Jul 1;28(4):258-275. PMID:&nbsp; 33871428<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33871428\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33871428\/<\/a><br>\n<\/p>\n<p><br><\/p>\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Penile Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>What Is New in the Pathologic Staging of Penile Carcinoma in the 8th Edition of AJCC TNM Model: Rationale for Changes With Practical Stage-by-stage Category Diagnostic Considerations.<\/strong><\/p>\n<p>Adv Anat Pathol. 2021 Jul 1;28(4):209-227. PMID:&nbsp; 34050061&nbsp;<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34050061\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34050061\/<\/a><\/p>\n<p><br><\/p>\n <h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Genitourinary sarcoma<\/h3>\n<p><br><\/p>\n<p><strong>Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup.<\/strong><\/p>\n<p>Mod Pathol. 2021 Apr 12. PMID:&nbsp; 33846547<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33846547\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33846547\/<\/a><br>\n<\/p>\n<p><br>\n<\/p>\n \n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Artificial Intelligence and Genitourinary Cancers<\/h3>\n<p> <\/p>\n<p><strong>Validating Whole Slide Imaging Systems for Diagnostic Purposes in Pathology: Guideline Update From the College of American Pathologists in Collaboration With the American Society for Clinical Pathology and the Association for Pathology Informatics. Evans et al.<\/strong><\/p>\n<p>Arch Pathol Lab Med. 2021 May 18. doi: 10.5858\/arpa.2020-0723-CP. Online ahead of print. PMID: 34003251<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34003251\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34003251\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Computationally Derived Cribriform Area Index from Prostate Cancer Hematoxylin and Eosin Images Is Associated with Biochemical Recurrence Following Radical Prostatectomy and Is Most Prognostic in Gleason Grade Group 2.<\/strong><\/p>\n<p>Leo et al. Eur Urol Focus. 2021 Apr 30:S2405-4569(21)00122-X. doi: 10.1016\/j.euf.2021.04.016. Online ahead of print. PMID: 33941504<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33941504\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/33941504\/<\/a><\/p>\n \n \n\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-9554\" class=\"elementor-tab-title\" data-tab=\"4\" role=\"tab\" aria-controls=\"elementor-tab-content-9554\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" href=\"\">Literature Watch 2021 Q4<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-9554\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-9554\"><h3 align=\"center\">Literature Watch &#038; News: Genitourinary Pathology (October 2021)<\/h3>\n<p align=\"center\">Sounak Gupta, MBBS, PhD and Rohit Mehra, MD.<\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Kidney Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>Different Fumarate Hydratase Gene Variants Are Associated With Distinct Cancer Phenotypes.<\/strong><\/p>\n<p><em>JCO Precision Oncology.<\/em>&nbsp;2021(5):1568-1578.<\/p>\n<p><a href=\"https:\/\/ascopubs.org\/doi\/full\/10.1200\/PO.21.00263\">https:\/\/ascopubs.org\/doi\/full\/10.1200\/PO.21.00263<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Co-existence of ESC-RCC, EVT, and LOT as synchronous and metachronous tumors in six patients with multifocal neoplasia but without clinical features of tuberous sclerosis complex.<\/strong><\/p>\n<p>Hum Pathol. 2021 Oct;116:1-11. doi: 10.1016\/j.humpath.2021.06.002. Epub 2021 Jun 19. PMID: 34153307.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34153307\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34153307\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Eosinophilic vacuolated tumor (EVT) of kidney demonstrates sporadic TSC\/MTOR mutations: next-generation sequencing multi-institutional study of 19 cases.<\/strong><\/p>\n<p>Mod Pathol. 2021 Sep 14. doi: 10.1038\/s41379-021-00923-6. Epub ahead of print. Erratum in: Mod Pathol. 2021 Oct 5;: PMID: 34521993.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34521993\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34521993\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Low-grade oncocytic renal tumor (LOT): mutations in mTOR pathway genes and low expression of FOXI1.<\/strong><\/p>\n<p>Mod Pathol. 2021 Sep 16. doi: 10.1038\/s41379-021-00906-7. Epub ahead of print. PMID: 34531523.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34531523\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34531523\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Germline and sporadic mTOR pathway mutations in low-grade oncocytic tumor of the kidney.<\/strong><\/p>\n<p>Mod Pathol. 2021 Sep 20. doi: 10.1038\/s41379-021-00896-6. Epub ahead of print. PMID: 34538873.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34538873\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34538873\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Papillary Renal Cell Carcinoma With Microcystic Architecture Is Strongly Associated With Extrarenal Invasion and Metastatic Disease,<\/strong><\/p>\n<p>The American Journal of Surgical Pathology: September 09, 2021. Epub ahead of print. doi: 10.1097\/PAS.0000000000001802.<\/p>\n<p><br>\n<\/p>\n<p><strong>Prognostic Significance of Percentage Necrosis in Clear Cell Renal Cell Carcinoma: A Clinicopathologic Study of Factors Associated With Survival in Pakistani Patients,<\/strong><\/p>\n<p>American Journal of Clinical Pathology, 2021; doi: 10.1093\/ajcp\/aqab136.<\/p>\n<p> <br> <\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Urinary Bladder Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>Utility of D2-40, Cytokeratin 5\/6, and High-Molecular-weight Cytokeratin (Clone 34&beta;E12) in Distinguishing Intraductal Spread of Urothelial Carcinoma From Prostatic Stromal Invasion.<\/strong><\/p>\n<p>Am J Surg Pathol. 2021 Sep 23. doi: 10.1097\/PAS.0000000000001816. Epub ahead of print. PMID: 34560681.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34560681\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34560681\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Upper urothelial tract High Grade Carcinoma: Comparison of Urine Cytology and DNA Methylation Analysis in Urinary Samples.<\/strong><\/p>\n<p>Hum Pathol. 2021 Sep 25:S0046-8177(21)00166-0. doi: 10.1016\/j.humpath.2021.09.007. Epub ahead of print. PMID: 34582934.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34582934\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34582934\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong><em>CD274<\/em>&nbsp;(<em>PD-L1<\/em>) Copy Number Changes (Gain) &amp; Response to Immune Checkpoint Blockade Therapy in Carcinomas of the Urinary Tract.<\/strong><\/p>\n<p>Bladder Cancer. Jan. 2021: 1 &ndash; 6. doi: 10.3233\/BLC-201532.<\/p>\n<p><br>\n<\/p>\n<p><strong>Reappraisal of HER2 Amplification in High-Grade Urothelial Carcinoma Based on 2018 ASCO\/CAP Clinical Practice Guidelines.<\/strong><\/p>\n<p>Am J Clin Pathol. 2021 Jun 14:aqab083. doi: 10.1093\/ajcp\/aqab083. Epub ahead of print. PMID: 34124742.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34124742\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34124742\/<\/a><\/p>\n<p><br>\n<\/p>\n<p> <br> <\/p>\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Prostate Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>Optimal Method for Reporting Prostate Cancer Grade in MRI-targeted Biopsies.<\/strong><\/p>\n<p>Am J Surg Pathol. 2021 Jun 10. doi: 10.1097\/PAS.0000000000001758. Epub ahead of print. PMID: 34115670.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34115670\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34115670\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Intraductal Adenocarcinoma of the Prostate With Cribriform or Papillary Ductal Morphology: Rare Biopsy Cases Lacking Associated Invasive High-grade Carcinoma.<\/strong><\/p>\n<p>Am J Surg Pathol. 2021 Oct 7. doi: 10.1097\/PAS.0000000000001819. Epub ahead of print. PMID: 34619708.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34619708\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34619708\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Diagnosis of &#8220;cribriform&#8221; prostatic adenocarcinoma: an interobserver reproducibility study among urologic pathologists with recommendations.<\/strong><\/p>\n<p>Am J Cancer Res. 2021 Aug 15;11(8):3990-4001. PMID: 34522463; PMCID: PMC8414383.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34522463\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34522463\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Prognostic value of cribriform size, percentage, and intraductal carcinoma in Gleason Score 7 prostate cancer with Cribriform Gleason Pattern 4.<\/strong><\/p>\n<p>Hum Pathol. 2021 Sep 17:S0046-8177(21)00163-5. doi: 10.1016\/j.humpath.2021.09.005. Epub ahead of print. PMID: 34543668.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34543668\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34543668\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><br>\n<\/p>\n \n <h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Testis Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>Somatic-type Malignancies in Testicular Germ Cell Tumors: A Clinicopathologic Study of 63 Cases.<\/strong><\/p>\n<p>Am J Surg Pathol. 2021 Aug 2. doi: 10.1097\/PAS.0000000000001789. Epub ahead of print. PMID: 34334690.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34334690\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34334690\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Testicular Germ-Cell Tumors with Spermatic Cord Involvement: A Retrospective International Multi-Institutional Experience.<\/strong><\/p>\n<p>Mod Pathol. 2021 Sep 9. doi: 10.1038\/s41379-021-00912-9. Epub ahead of print. PMID: 34504308.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34504308\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34504308\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Adenocarcinoma of the Rete Testis: Seven Additional Cases, Including Exclusively and Predominantly Intrarete Tumors.<\/strong><\/p>\n<p>Am J Surg Pathol. 2021 Jul 1. doi: 10.1097\/PAS.0000000000001771. Epub ahead of print. PMID: 34224412.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34224412\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34224412\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>Nodular Maturation of the Testis,<\/strong><\/p>\n<p>The American Journal of Surgical Pathology: July 12, 2021. Epub ahead of print. doi: 10.1097\/PAS.0000000000001775.<\/p>\n<p> <br> <\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Penile Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>A comparative study of AJCC and the modified staging system in pT2\/pT3 penile squamous cell carcinoma- A validation on an external dataset.<\/strong><\/p>\n<p>Histopathology. 2021 Sep 29. doi: 10.1111\/his.14575. Epub ahead of print. PMID: 34586682.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34586682\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34586682\/<\/a><\/p>\n<p><br><\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Adrenal Tumors<\/h3>\n<p><strong>SMARCA4-Deficient Undifferentiated Tumor Diagnosed on Adrenal Sampling.<\/strong><\/p>\n<p>Am J Clin Pathol. 2021 Aug 31:aqab101. doi: 10.1093\/ajcp\/aqab101. Epub ahead of print. PMID: 34463317.<\/p>\n<p> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34463317\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34463317\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><strong>TERT Copy Number Alterations, Promoter Mutations and Rearrangements in Adrenocortical Carcinomas.<\/strong><\/p>\n<p>Endocr Pathol. 2021 Sep 22. doi: 10.1007\/s12022-021-09691-0. Epub ahead of print. PMID: 34549366.<\/p>\n<p> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34549366\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34549366\/<\/a><\/p>\n<p><br>\n<\/p>\n<p><br>\n<\/p>\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Artificial Intelligence and Genitourinary Cancers<\/h3>\n\n<p> <br> <\/p>\n<p><strong>Artificial Intelligence in Pathology.<\/strong><\/p>\n<p>Am J Pathol. 2021 Oct;191(10):1670-1672. doi: 10.1016\/j.ajpath.2021.07.011. Epub 2021 Aug 13. PMID: 34391718.<\/p>\n<p> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34391718\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34391718\/<\/a><\/p>\n<p><br>\n<\/p>\n<p> <strong>Validating Whole Slide Imaging Systems for Diagnostic Purposes in Pathology: Guideline Update From the College of American Pathologists in Collaboration With the American Society for Clinical Pathology and the Association for Pathology Informatics.<\/strong><\/p>\n<p>Arch Pathol Lab Med. 2021 May 18. doi: 10.5858\/arpa.2020-0723-CP. Online ahead of print. PMID: 34003251.<\/p>\n<p> <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34003251\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/34003251\/<\/a><\/p>\n<br>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Literature Watch 2020 Q1 Literature Watch &amp; News: Genitourinary Pathology (2020 Q1) Sounak Gupta, MBBS, PhD and Rohit Mehra, MD Renal Cancer Recurrent KRAS mutations in papillary renal neoplasm with reverse polarity. Al-Obaidy KI et al. Modern Pathology. 2019 Sep 18. PMID: 31534204.\u00a0https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31534204 &#8211; This study, senior authored by the late Dr. David Grignon, a<br \/><a class=\"moretag\" href=\"https:\/\/iboblr.in\/gupathsociety\/literarure-watch-2021\/\">+ Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/page-fullwidth_template.php","meta":{"pmpro_default_level":0,"footnotes":""},"class_list":["post-5494","page","type-page","status-publish","hentry","pmpro-has-access"],"_links":{"self":[{"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/pages\/5494","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/comments?post=5494"}],"version-history":[{"count":31,"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/pages\/5494\/revisions"}],"predecessor-version":[{"id":8042,"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/pages\/5494\/revisions\/8042"}],"wp:attachment":[{"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/media?parent=5494"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}