{"id":5492,"date":"2022-04-20T17:32:11","date_gmt":"2022-04-20T17:32:11","guid":{"rendered":"https:\/\/iboblr.in\/gupathsociety\/?page_id=5492"},"modified":"2022-10-28T06:17:41","modified_gmt":"2022-10-28T06:17:41","slug":"literature-watch-2020","status":"publish","type":"page","link":"https:\/\/iboblr.in\/gupathsociety\/literature-watch-2020\/","title":{"rendered":"Literature Watch 2020"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"5492\" class=\"elementor elementor-5492\" data-elementor-settings=\"[]\">\n\t\t\t\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-91c2d89 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"91c2d89\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5d2f79b\" data-id=\"5d2f79b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1a694d4 elementor-widget elementor-widget-html\" data-id=\"1a694d4\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<script>\r\njQuery(document).ready(function($) {\r\nvar delay = 100; setTimeout(function() {\r\n$('.elementor-tab-title').removeClass('elementor-active');\r\n $('.elementor-tab-content').css('display', 'none'); }, delay);\r\n});\r\n<\/script>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-81d6189 elementor-widget elementor-widget-heading\" data-id=\"81d6189\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.5.6 - 28-02-2022 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\"> Literature Watch & News: Genitourinary Pathology (2020 Q1)<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-606da2f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"606da2f\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7712860\" data-id=\"7712860\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-808ad3c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"808ad3c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-b1f1ce4\" data-id=\"b1f1ce4\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0eb5087 elementor-widget elementor-widget-sidebar\" data-id=\"0eb5087\" data-element_type=\"widget\" data-widget_type=\"sidebar.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div id=\"block-5\" class=\"widget widget_block\" data-widget-id=\"block-5\"><div class=\"widget_wrap\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link\" href=\"https:\/\/iboblr.in\/gupathsociety\/literature-watch-2022\/\">Literature Watch 2022<\/a><\/div>\n<\/div>\n<\/div><\/div>\n<span class=\"widget_corner\"><\/span><\/div><\/div><div id=\"block-25\" class=\"widget widget_block\" data-widget-id=\"block-25\"><div class=\"widget_wrap\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<span class=\"widget_corner\"><\/span><\/div><\/div><div id=\"block-6\" class=\"widget widget_block\" data-widget-id=\"block-6\"><div class=\"widget_wrap\">\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link\" href=\"https:\/\/iboblr.in\/gupathsociety\/literarure-watch-2021\/\">Literature Watch 2021<\/a><\/div>\n<\/div>\n<\/div><\/div>\n<span class=\"widget_corner\"><\/span><\/div><\/div><div id=\"block-26\" class=\"widget widget_block\" data-widget-id=\"block-26\"><div class=\"widget_wrap\">\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n<span class=\"widget_corner\"><\/span><\/div><\/div><div id=\"block-24\" class=\"widget widget_block\" data-widget-id=\"block-24\"><div class=\"widget_wrap\">\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link\" href=\"https:\/\/iboblr.in\/gupathsociety\/literature-watch-2020\/\">Literature Watch 2020<\/a><\/div>\n<\/div>\n<span class=\"widget_corner\"><\/span><\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-2566ed3\" data-id=\"2566ed3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-25903e1 elementor-widget elementor-widget-accordion\" data-id=\"25903e1\" data-element_type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.5.6 - 28-02-2022 *\/\n.elementor-accordion{text-align:left}.elementor-accordion .elementor-accordion-item{border:1px solid #d4d4d4}.elementor-accordion .elementor-accordion-item+.elementor-accordion-item{border-top:none}.elementor-accordion .elementor-tab-title{margin:0;padding:15px 20px;font-weight:700;line-height:1;cursor:pointer;outline:none}.elementor-accordion .elementor-tab-title .elementor-accordion-icon{display:inline-block;width:1.5em}.elementor-accordion .elementor-tab-title .elementor-accordion-icon svg{width:1em;height:1em}.elementor-accordion .elementor-tab-title .elementor-accordion-icon.elementor-accordion-icon-right{float:right;text-align:right}.elementor-accordion .elementor-tab-title .elementor-accordion-icon.elementor-accordion-icon-left{float:left;text-align:left}.elementor-accordion .elementor-tab-title .elementor-accordion-icon .elementor-accordion-icon-closed{display:block}.elementor-accordion .elementor-tab-title .elementor-accordion-icon .elementor-accordion-icon-opened,.elementor-accordion .elementor-tab-title.elementor-active .elementor-accordion-icon-closed{display:none}.elementor-accordion .elementor-tab-title.elementor-active .elementor-accordion-icon-opened{display:block}.elementor-accordion .elementor-tab-content{display:none;padding:15px 20px;border-top:1px solid #d4d4d4}@media (max-width:767px){.elementor-accordion .elementor-tab-title{padding:12px 15px}.elementor-accordion .elementor-tab-title .elementor-accordion-icon{width:1.2em}.elementor-accordion .elementor-tab-content{padding:7px 15px}}<\/style>\t\t<div class=\"elementor-accordion\" role=\"tablist\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-3931\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"tab\" aria-controls=\"elementor-tab-content-3931\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" href=\"\">Literature Watch 2020 Q1<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-3931\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-3931\"><h3 style=\"background-color: #e1e1e1; margin: 10px 0px 10px 0px; padding: 10px 0px 10px 10px;\">Renal Cancer<\/h3><p><strong>Recurrent KRAS mutations in papillary renal neoplasm with reverse polarity.<\/strong><\/p><p>&#8211; Al-Obaidy KI et al. Modern Pathology. 2019 Sep 18. PMID: 31534204.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31534204\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31534204<\/a><\/p><p>This study, senior authored by the late Dr. David Grignon, a giant in the field of genitourinary pathology, is another seminal work which characterizes the morphologic features and molecular underpinnings of a unique variant of papillary renal cell carcinoma.<\/p><p><strong>&#8220;Renal Cell Carcinoma With Leiomyomatous Stroma&#8221; Harbor Somatic Mutations of TSC1, TSC2, MTOR, and\/or ELOC (TCEB1): Clinicopathologic and Molecular Characterization of 18 Sporadic Tumors Supports a Distinct Entity.<\/strong><\/p><p>Shah RB et al. American Journal of Surgical Pathology. 2019 Dec 31. PMID: 31850909.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31850909\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31850909<\/a><\/p><p>&#8211; The authors of this study provide insight into the characterization of renal neoplasms that are morphologically enriched for the presence of leiomyomatous stroma, including underlying molecular alterations.<\/p><h3 style=\"background-color: #e1e1e1; margin: 10px 0px 10px 0px; padding: 10px 0px 10px 10px;\">Bladder Cancer<\/h3><p><b>BCG is extensively used for the management of non-muscle invasive bladder cancer. However, significant shortages are anticipated in the coming year.<\/b><\/p><p>This has been highlighted by the Bladder Cancer Advocacy Network (BCAN): <a href=\"https:\/\/bcan.org\/bcg-shortage-bladder-cancer\/#1560949642874-aab3abc1-db8\" target=\"_blank\" rel=\"noopener\">https:\/\/bcan.org\/bcg-shortage-bladder-cancer\/#1560949642874-aab3abc1-db8e<\/a><\/p><h3 style=\"background-color: #e1e1e1; margin: 10px 0px 10px 0px; padding: 10px 0px 10px 10px;\">Prostate Cancer<\/h3><p><strong>When and How Should Active Surveillance for Prostate Cancer be De-Escalated?<\/strong><\/p><p>Rajwa P et al. European Urology Focus. 2020.\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.euf.2020.01.001\">https:\/\/doi.org\/10.1016\/j.euf.2020.01.001<\/a><\/p><p>&#8211; Herein, the authors review available evidence and guidelines addressing transitions from active to passive monitoring for patients with low-risk prostate cancer.<\/p><p><strong>Reporting Practices and Resource Utilization in the Era of Intraductal Carcinoma of the Prostate: A Survey of Genitourinary Subspecialists.<\/strong><\/p><p>Gandhi JS et al. American Journal of Surgical Pathology. 2019 Dec 23. PMID: 31876580.<\/p><p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31876580\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31876580<\/a><\/p><p>&#8211; This report summarizes best practice recommendations related to diagnosis and reporting practices pertaining to intraductal carcinoma of the prostate.<\/p><p><strong>Management of Patients with Advanced Prostate Cancer: Report of the Advanced Prostate Cancer Consensus Conference 2019.<\/strong><\/p><p>Gillessen S et al. European Urology. 2020 Jan 27. PMID: 32001144.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32001144\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32001144<\/a><\/p><p>&#8211; This study summarizes expert opinion related to common issues and controversies regarding the management of patients with advanced prostate cancer, including metastatic hormone-sensitive and metastatic castration-resistant prostate cancer.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-3932\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"tab\" aria-controls=\"elementor-tab-content-3932\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" href=\"\">Literature Watch 2020 Q2<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-3932\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-3932\"> <h3 align=\"center\"> Literature Watch &#038; News: Genitourinary Pathology (April 2020- Lockdown edition)<\/h3>\n<p align=\"center\">Sounak Gupta, MBBS, PhD and Rohit Mehra, MD.<\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Renal Cancer<\/h3>\n \n\n<p><strong>MiT family translocation renal cell carcinoma. <\/strong><\/p>\n<p>Argani P. Semin Diagn Pathol. 2015 Mar;32(2):103-13. Review. PMID: 25758327.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25758327\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25758327<\/a><\/p>\n<p>&#8211; This review, authored by Dr. Pedram Argani, highlights the morphologic, translational and biologic features of MiT family aberration renal cell carcinoma.<\/p>\n\n\n<p><strong> Contemporary Renal Tumor Categorization With Biomarker and Translational Updates: A Practical Review. <\/strong><\/p>\n<p>Taylor et al. Arch Pathol Lab Med. 2019 Dec;143(12):1477-1491. Review. PMID: 31765248. &nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31765248\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31765248<\/a><\/p>\n<p>&#8211; The authors of this study provide insight into the evolutionary biomarker landscape of renal cell carcinoma, incorporating established markers with upcoming markers of clinical potential.<\/p>\n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Bladder Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>Updates on the Genomics of Bladder Cancer and Novel Molecular Taxonomy. <\/strong><\/p> \n <p>Al-Ahmadie H, Netto GJ. Adv Anat Pathol. 2020 Jan;27(1):36-43. Review. PMID: 31743118.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31743118\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31743118<\/a><\/p>\n<p>This review provides an update on the recent advances in the molecular characterization and novel molecular taxonomy of urothelial carcinoma and its histologic variants.<\/p>\n \n\n \n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Prostate Cancer<\/h3>\n \n<p><strong>Knowing what&#8217;s growing: Why ductal and intraductal prostate cancer matter.<\/strong><\/p>\n<p>Lawrence et al. Sci Transl Med. 2020 Mar 4;12(533). Review. PMID: 32132214.<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32132214\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32132214\/<\/a><\/p>\n<p>&#8211; This review summarizes the pathologic, clinical and translational implications of ductal prostate cancer and intraductal prostate cancer.<\/p>\n<p><br>\n<\/p>\n\n<p><strong>Towards precision oncology in advanced prostate cancer. Ku et al. Nat Rev Urol. 2019 Nov;16(11):645-654. Review. PMID: 31591549. <\/strong><\/p> \n<p><a href=\" https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31591549\"> https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31591549<\/a><\/p>\n<p>This review summarizes expert opinion related to concepts, common management issues and clinical applications for patients with advanced prostate cancer. <\/p>\n \n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Testis Cancer<\/h3>\n<p><strong>Recently Described and Clinically Important Entities in Testis Tumors: A Selective Review of Changes Incorporated Into the 2016 Classification of the World Health Organization. <\/strong><\/p>\n<p>Ulbright TM. Arch Pathol Lab Med. 2019 Jun;143(6):711-721. Review. PMID: 29949388.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29949388\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29949388\/<\/a><\/p>\n<p>&#8211; This review summarizes some common testicular pathologies with their clinical implications especially in light of the WHO classification of genitourinary tumors.<\/p>\n \n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Penile Cancer<\/h3>\n<p><strong>Pathology of Invasive and Intraepithelial Penile Neoplasia. <\/strong><\/p>\n<p>Canete-Portillo et al. Eur Urol Focus. 2019 Sep;5(5):713-717. Review. PMID: 31288989. <\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31288989\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31288989<\/a><\/p>\n<p>&#8211; This review summarizes an updated approach towards classification of penile intraepithelial neoplasia and penile invasive carcinoma.<\/p>\n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Miscellaneous<\/h3>\n<p><strong>Next generation immunohistochemistry: Emerging substitutes to genetic testing?<\/strong><\/p>\n<p>Andrici et al. Semin Diagn Pathol. 2018 May;35(3):161-169. Review.<\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28662997\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28662997<\/a><\/p>\n<p>PMID: 28662997<\/p>\n<p>&#8211; This review elaborates on the utility of immunohistochemistry in detection of syndromic neoplasia (including genitourinary) from a surgical pathology perspective.<\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Complimentary Courses<\/h3>\n\n<strong>USCAP:&nbsp;<\/strong>Urologic Pathology, Course Director: Adeboye O. Osunkoya, MD<br>\n<strong>Code:<\/strong>&nbsp;USCAPnvzcxw<br>\n<strong>&ldquo;Complimentary Access to eLearning from USCAP<\/strong>\n\n \n<p>In response to the impact of the COVID-19 pandemic on pathology education, USCAP is currently providing complimentary access to eLearning modules<\/p>\n<p><a href=\"https:\/\/www.pathlms.com\/uscap\/courses\/14759\">https:\/\/www.pathlms.com\/uscap\/courses\/14759<\/a><\/p>\n \n<p>This includes a section on Urologic Pathology, a course that is directed by Dr. Adeboye O. Osunkoya, MD, and includes sections on high yield prostate and bladder pathology (code: USCAPnvzcxw).\u201d<\/p>\n\n <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-3933\" class=\"elementor-tab-title\" data-tab=\"3\" role=\"tab\" aria-controls=\"elementor-tab-content-3933\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" href=\"\">Literature Watch 2020 Q3<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-3933\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-3933\"><h3 align=\"center\"> Literature Watch &#038; News: Genitourinary Pathology (July 2020)<\/h3>\n<p align=\"center\">Sounak Gupta, MBBS, PhD and Rohit Mehra, MD.<\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Renal Cancer<\/h3>\n \n\n<p><strong>ALK Rearranged Renal Cell Carcinoma (ALK-RCC): A Multi-Institutional Study of Twelve Cases With Identification of Novel Partner Genes CLIP1, KIF5B and KIAA1217.<\/strong><\/p>\n<p>Kuroda et al. Mod Pathol. 2020 May 28. PMID: 32467651<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32467651\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32467651\/<\/a><\/p>\n<p>&#8211; This study describes the clinicopathologic features of a series of 12 ALK rearranged renal cell carcinomas, including diverse morphologic features, and advocates for ALK immunohistochemistry-based screening of &#8220;unclassifiable RCCs&#8221;.<\/p>\n\n\n<p><strong> Next-generation RNA Sequencing-based Biomarker Characterization of Chromophobe Renal Cell Carcinoma and Related Oncocytic Neoplasms. <\/strong><\/p>\n<p>Skala et al. Eur Urol. 2020 Jul;78(1):63-74. PMID: 32299640<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32299640\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32299640\/<\/a><\/p>\n<p>&#8211; Herein, the authors evaluated RNA sequencing data from The Cancer Genome Atlas project to identify chromophobe renal cell carcinoma-specific biomarkers such as FOXI1, which are found to be localized to the intercalated cells of the distal nephron in non-neoplastic kidney tissue.<\/p>\n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Bladder Cancer<\/h3>\n<p><br>\n<\/p>\n<p><strong>European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.<\/strong><\/p> \n <p>Roupret et al. Eur Urol. 2020 Jun 24;S0302-2838(20)30427-9. PMID: 32593530 <\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32593530\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32593530\/<\/a><\/p>\n<p>This manuscript summarizes the recommendations of the European Association of Urology (EAU) Guidelines Panel on current evidence-based management of Upper Urinary Tract Urothelial Carcinoma (UTUC) for routine clinical practice.<\/p>\n<p><br><\/p>\n\n <p><strong>Variant Morphology and Random Chromosomal Integration of BK Polyomavirus in Posttransplant Urothelial Carcinomas.<\/strong><\/p>\n<p>Bertz et al. Mod Pathol. 2020 Jul;33(7):1433-1442. PMID: 32047230<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32047230\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32047230\/<\/a><\/p>\n<p>&#8211; Herein, the authors have studied the pathogenic role of BK polyoma virus in the development of urothelial carcinoma following immune suppression in solid organ transplant recipients.<\/p>\n<p><br>\n<\/p>\n\n \n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Prostate Cancer<\/h3>\n \n<p><strong>The 2019 Genitourinary Pathology Society (GUPS) White Paper on Contemporary Grading of Prostate Cancer.<\/strong><\/p>\n<p>Epstein et al. Arch Pathol Lab Med . 2020 Jun 26. PMID: 32589068<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32589068\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32589068\/<\/a><\/p>\n<p>&#8211; This manuscript summarizes the Genitourinary Pathology Society (GUPS) recommendations pertaining to contemporary grading of prostate cancer based on a critical review of the literature along with pathology and clinician surveys.<\/p>\n<p><br><\/p>\n\n<p><strong>The 2019 International Society of Urological Pathology (ISUP) Consensus Conference on Grading of Prostatic Carcinoma.<\/strong><\/p> \n<p>Van Leenders et al. Am J Surg Pathol. 2020 May 26. PMID: 32459716 <\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32459716\/\"> https:\/\/pubmed.ncbi.nlm.nih.gov\/32459716\/<\/a><\/p>\n<p>This manuscript summarizes the International Society of Urological Pathology (ISUP) recommendations pertaining to contemporary grading of prostate cancer.<\/p>\n<p><br><\/p>\n\n<p><strong>Role of Changes in Magnetic Resonance Imaging or Clinical Stage in Evaluation of Disease Progression for Men with Prostate Cancer on Active Surveillance.<\/strong><\/p> \n<p>Chestnut et al. Eur Urol. 2020 Apr;77(4):501-507. PMID:  31874726 <\/p>\n<p><a href=\"httpshttps:\/\/pubmed.ncbi.nlm.nih.gov\/31874726\/\"> https:\/\/pubmed.ncbi.nlm.nih.gov\/31874726\/<\/a><\/p>\n<p>Herein, the authors compare active surveillance protocols based on MRI or clinical stage changes compared with scheduled systematic biopsies to detect reclassification to grade group \u22652 disease.<\/p>\n\n\n \n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Testis Cancer<\/h3>\n<p><strong>Appendageal Tumors and Tumor-Like Lesions of the Testis and Paratestis: A 32-Years of Experience at a Single Institution.<\/strong><\/p>\n<p>l-Obaidy et al. Human Pathology, 2020 June 30; Electronic publication, ahead of print). PMID:  32619438<\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0046817720301222\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0046817720301222<\/a><\/p>\n<p>&#8211; This report summarizes a single institution experience of over 30 years pertaining to paratesticular tumors and tumors of testicular appendages.<\/p>\n <p><br><\/p>\n \n<p><strong>Bilateral Synchronous Testicular Germ Cell Tumors in Children: Case Report and Review of the Literature.<\/strong><\/p>\n<p>Kebudi et al. Urology. 2020 Jun;140:155-158. PMID: 32199873<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32199873\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32199873\/<\/a><\/p>\n<p>&#8211; This report highlights a case and summarizes relevant literature pertaining to bilateral testicular tumors in pediatric patients.<\/p>\n <p><br><\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Penile Cancer<\/h3>\n<p><strong>The Molecular Pathogenesis of Penile Carcinoma-Current Developments and Understanding.<\/strong><\/p>\n<p>Emmanuel et al. Virchows Arch. 2019 Oct;475(4):397-405. PMID: 31243533<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31243533\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31243533\/<\/a><\/p>\n<p>&#8211; This review summarizes the literature pertaining to molecular drivers that govern penile carcinogenesis and their underlying prognostic and therapeutic importance.<\/p>\n<p><br><\/p>\n \n<p><strong>A Modified Histopathologic Staging in Penile Squamous Cell Carcinoma Predicts Nodal Metastasis and Outcome Better Than the Current AJCC Staging. <\/strong><\/p>\n<p>Sali et al. Am J Surg Pathol. 2020 Apr 14. PMID: 32301753<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32301753\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32301753\/<\/a><\/p>\n<p>&#8211; Herein, the authors have reviewed 142 cases of penile squamous cell carcinoma.  This study evaluates the current AJCC staging system and suggests proposed modifications.<\/p>\n<p><br><\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">COVID-19<\/h3>\n<p><strong>Prioritizing Urological Surgery in the COVID-19 Era: A Global Reflection on Guidelines.<\/strong><\/p>\n<p>Gravas et al. Eur Urol Focus. 2020 Jun 15;S2405-4569(20)30164-4. PMID:  32571743<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32571743\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32571743\/<\/a><\/p>\n<p>&#8211; This report evaluates the prioritization and management of urological procedures during the COVID-19 pandemic.<\/p>\n<p><br><\/p>\n \n \n<p>The Multifaceted Long-Term Effects of the COVID-19 Pandemic on Urology.<\/p>\n<p>Morlacco et al. Nat Rev Urol. 2020 Jul;17(7):365-367. PMID:  32377015<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32377015\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32377015\/<\/a><\/p>\n \n<p>This review aims to discuss COVID related effects for patients and Urology.<\/p>\n\n <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-3934\" class=\"elementor-tab-title\" data-tab=\"4\" role=\"tab\" aria-controls=\"elementor-tab-content-3934\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><i class=\"fas fa-plus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><i class=\"fas fa-minus\"><\/i><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" href=\"\">Literature Watch 2020 Q4<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-3934\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-3934\"><h3 align=\"center\"> Literature Watch &#038; News: Genitourinary Pathology (October 2020)<\/h3>\n<p align=\"center\">Sounak Gupta, MBBS, PhD and Rohit Mehra, MD<\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Renal Cancer<\/h3>\n \n\n<p><strong>Adverse histology, homozygous loss of CDKN2A\/B, and complex genomic alterations in locally advanced\/metastatic renal mucinous tubular and spindle cell carcinoma.<\/strong> <\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41379-020-00667-9\">https:\/\/www.nature.com\/articles\/s41379-020-00667-9<\/a><\/p>\n<p>Yang et al. Mod Pathol. 2020 Sep 2. [Online ahead of print]. PMID:  32879414<\/p>\n<p><br><\/p>\n\n<p><strong> MET alterations in biphasic squamoid alveolar papillary renal cell carcinomas and clinicopathological features.<\/strong><\/p> \n<p><a href=\"https:\/\/www.nature.com\/articles\/s41379-020-0645-6\">https:\/\/www.nature.com\/articles\/s41379-020-0645-6<\/a><\/p>\n<p>Denize et al. Mod Pathol. 2020 Aug 7. [Online ahead of print]. PMID:  32770124<\/p>\n<p><br><\/p>\n \n \n<p><strong>Distinguishing Benign Renal Tumors with an Oncocytic Gene Expression (ONEX) Classifier.<\/strong><\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0302283820307090?via%3Dihub\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0302283820307090?via%3Dihub<\/a><\/p>\n<p>McGillivray et al. Eur Urol. 2020 Sep 21;S0302-2838(20)30709-0.[Online ahead of print]. PMID:&nbsp; 32972793<\/p>\n\n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Bladder Cancer<\/h3>\n<p><br>\n<\/p>\n \n\n \n<p><strong>Primary Female Urethral Carcinoma: Proposed Staging Modifications Based on Assessment of Female Urethral Histology and Analysis of a Large Series of Female Urethral Carcinomas.<\/strong><\/p>\n<p><a href=\"https:\/\/journals.lww.com\/ajsp\/Abstract\/9000\/Primary_Female_Urethral_Carcinoma__Proposed.97360.aspx\">https:\/\/journals.lww.com\/ajsp\/Abstract\/9000\/Primary_Female_Urethral_Carcinoma__Proposed.97360.aspx<\/a><\/p>\nAron et al. Am J Surg Pathol. 2020 Aug 28. [Online ahead of print]. PMID:&nbsp; 32868524\n<p>&nbsp;<\/p>\n<p><strong>Clear Cell Adenocarcinoma in Men: A Series of 15 Cases.<\/strong><\/p>\n<p><a href=\"https:\/\/journals.lww.com\/ajsp\/Abstract\/9000\/Clear_Cell_Adenocarcinoma_in_Men__A_Series_of_15.97349.aspx\">https:\/\/journals.lww.com\/ajsp\/Abstract\/9000\/Clear_Cell_Adenocarcinoma_in_Men__A_Series_of_15.97349.aspx<\/a><\/p>\n<p>Grosser et al. Am J Surg Pathol. 2020 Sep 21. [Online ahead of print]. PMID:&nbsp; 32960833&nbsp;<\/p>\n<p><strong><br>\n<\/strong><\/p>\n<p><strong>Intestinal metaplasia of the urinary tract harbors potentially oncogenic genetic variants.<\/strong><\/p>\n<p><a href=\"https:\/\/www.nature.com\/articles\/s41379-020-00655-z\">https:\/\/www.nature.com\/articles\/s41379-020-00655-z<\/a><\/p>\n<p>Acosta et al. Mod Pathol. 2020 Aug 28. [Online ahead of print]. PMID:&nbsp; 32860003<\/p>\n\n\n\n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Prostate Cancer<\/h3>\n \n \n \n\n<p><strong>Clinicopathologic Study of Gleason Pattern 5 Prostatic Adenocarcinoma With &ldquo;Single-cell&rdquo; Growth Reveals 2 Distinct Types, One With &ldquo;Plasmacytoid&rdquo; Features.<\/strong><\/p>\n<p><a href=\"https:\/\/journals.lww.com\/ajsp\/Abstract\/9000\/Clinicopathologic_Study_of_Gleason_Pattern_5.97344.aspx\">https:\/\/journals.lww.com\/ajsp\/Abstract\/9000\/Clinicopathologic_Study_of_Gleason_Pattern_5.97344.aspx<\/a><\/p>\n<p>Nguyen et al. Am J Surg Pathol. 2020 Sep 25. [Online ahead of print]. PMID:&nbsp; 32991340<\/p>\n<p><br>\n<\/p>\n<p><strong>PIN&#8208;like ductal carcinoma of the prostate has frequent activating RAS\/RAF mutations.<\/strong><\/p>\n<p><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/his.14224\">https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/his.14224<\/a><\/p>\n<p>Kaur et al. Histopathology. 2020 Aug 2.&nbsp; [Online ahead of print].&nbsp; PMID:&nbsp; 32740981<\/p>\n<p><strong><br>\n<\/strong><\/p>\n<p><strong>Head to head: should the intraductal component of invasive prostate cancer be graded?<\/strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/his.14216\">https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/his.14216<\/a><\/p>\n<p>Varma and Epstein. Histopathology. 2020 Jul 21.&nbsp; [Online ahead of print]. PMID:&nbsp; 32692448&nbsp;<\/p>\n\n\n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Testis Cancer<\/h3>\n \n <p><strong>Hepatoid Teratoma, Hepatoid Yolk Sac Tumor, and Hepatocellular Carcinoma: A Morphologic and Immunohistochemical Study of 30 Cases.<\/strong><\/p>\n <p><a href=\"https:\/\/journals.lww.com\/ajsp\/Abstract\/9000\/Hepatoid_Teratoma,_Hepatoid_Yolk_Sac_Tumor,_and.97346.aspx\">https:\/\/journals.lww.com\/ajsp\/Abstract\/9000\/Hepatoid_Teratoma,_Hepatoid_Yolk_Sac_Tumor,_and.97346.aspx<\/a><\/p>\n <p>Al-Obaidy et al. Am J Surg Pathol. 2020 Sep 25. [Online ahead of print]. PMID:&nbsp; 32991342<\/p>\n <p><strong><br>\n <\/strong><\/p>\n <p><strong>The detection of isochromosome i[12p] in malignant germ cell tumours and tumours with somatic malignant transformation using qPCR.<\/strong><\/p>\n <p><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/his.14258\">https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/his.14258<\/a><\/p>\n <p>Fichtner et al. Histopathology. 2020 Sep 24.&nbsp; [Online ahead of print].&nbsp; PMID:&nbsp; 32970854<\/p>\n\n\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">Penile Cancer<\/h3>\n \n \n<p><strong>Peyronie disease: a clinicopathologic study of 71 cases with emphasis on histopathologic patterns and prevalent metaplastic ossification.<\/strong><\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0046817720301362?via%3Dihub\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0046817720301362?via%3Dihub<\/a><\/p>\n<p>Hatfield et al. Hum Pathol. 2020 Jul 15;104:9-17. PMID:  32681945<\/p>\n<p><br><\/p>\n\n\n<h3 style=\"background-color:#e1e1e1; margin:10px 0px 10px 0px; padding:10px 0px 10px 10px;\">COVID-19<\/h3>\n<p><strong>The Impact of the COVID-19 Pandemic on Genitourinary Cancer Care: Re-envisioning the Future.<\/strong><\/p>\n<p><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S030228382030676X?via%3Dihub\">https:\/\/www.sciencedirect.com\/science\/article\/pii\/S030228382030676X?via%3Dihub<\/a><\/p>\n<p>Wallis et al. Eur Urol. 2020 Sep 3;S0302-2838(20)30676-X. [Online ahead of print]. PMID: 32893062<\/p>\n<p><br><\/p>\n \n <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-787de17 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"787de17\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-e883304\" data-id=\"e883304\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-25efc56\" data-id=\"25efc56\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e9093c4 elementor-widget elementor-widget-text-editor\" data-id=\"e9093c4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.5.6 - 28-02-2022 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#818a91;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#818a91;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Literature Watch &#038; News: Genitourinary Pathology (2020 Q1) Literature Watch 2020 Q1 Renal Cancer Recurrent KRAS mutations in papillary renal neoplasm with reverse polarity. &#8211; Al-Obaidy KI et al. Modern Pathology. 2019 Sep 18. PMID: 31534204.\u00a0https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31534204 This study, senior authored by the late Dr. David Grignon, a giant in the field of genitourinary pathology, is<br \/><a class=\"moretag\" href=\"https:\/\/iboblr.in\/gupathsociety\/literature-watch-2020\/\">+ Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"templates\/page-fullwidth_template.php","meta":{"pmpro_default_level":0,"footnotes":""},"class_list":["post-5492","page","type-page","status-publish","hentry","pmpro-has-access"],"_links":{"self":[{"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/pages\/5492","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/comments?post=5492"}],"version-history":[{"count":22,"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/pages\/5492\/revisions"}],"predecessor-version":[{"id":8045,"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/pages\/5492\/revisions\/8045"}],"wp:attachment":[{"href":"https:\/\/iboblr.in\/gupathsociety\/wp-json\/wp\/v2\/media?parent=5492"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}